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The OMS28 porin Family [Function: Non-specific diffusion channels] Seed alignment | Full alignment | Pfam page | TC-DB page

Members of this family are small (28 kDa) surface exposed proteins found in Borrelia. They exhibit channel activity, which indicates their role as porins. However, prediction methods do not corroborate to a large ß sheet content, a fact that may indicates the multimeric nature of the presumable ß-barrel. Recent contradicting evidence though suggest that Oms28 could be a periplasmic outer membrane-associated protein.

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Literature references

Borrelia burgdorferi BBA74, a periplasmic protein associated with the outer membrane, lacks porin-like properties
J Bacteriol. 2007 Mar;189(5):2063-8. doi: 10.1128/JB.01239-06. Epub 2006 Dec 22.
PMID: 17189354

Porin activity of the native and recombinant outer membrane protein Oms28 of Borrelia burgdorferi
J Bacteriol. 1996 Aug;178(16):4909-18. doi: 10.1128/jb.178.16.4909-4918.1996.
PMID: 8759855

Elixir UTH dib compgen