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The Serpulina hyodysenteriae variable surface protein Family [Function: Unknown] Seed alignment | Full alignment | Pfam page

This family consists of various surface-exposed proteins identified in Serpulina hyodysenteriae, a spirochete which is the etiologic agent of swine dysentery. The genes are located in two sets of tandemly linked alleles. The encoded proteins are surface-exposed and prediction methods corroborate to the existence of a ß-barrel structure.

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Literature references

The complete genome sequence of the pathogenic intestinal spirochete Brachyspira pilosicoli and comparison with other Brachyspira genomes
PLoS One. 2010 Jul 6;5(7):e11455. doi: 10.1371/journal.pone.0011455.
PMID: 20625514

Brachyspira hyodysenteriae contains eight linked gene copies related to an expressed 39-kDa surface protein
Microbes Infect. 2003 Jan;5(1):1-6. doi: 10.1016/s1286-4579(02)00048-5.
PMID: 12593966

Sequence characterization of two new members of a multi-gene family in Serpulina hyodysenteriae (B204) with homology to a 39 kDa surface exposed protein: vspC and D
Vet Microbiol. 1999 Aug 31;68(3-4):273-83. doi: 10.1016/s0378-1135(99)00104-2.
PMID: 10510046

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