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The Treponema Porin Major Surface Protein (TP-MSP) Family [Function: Unknown] Seed alignment | Full alignment | TC-DB page
This family consists of the major outer sneath proteins of Treponema lecithinolyticum and Treponema maltophilum. These proteins are localized in the outer membrane and form heat-modifiable, detergent and trypsin-stable complexes, suggesting a ß-barrel structure. However, they have not shown any channel activity and no sequence similarity to the MspA of Treponema denticola, therefore are chosen to comprise a different family.
Cloning and characterization of a gene (mspA) encoding the major sheath protein of Treponema maltophilum ATCC 51939(T)
J Bacteriol. 1999 Feb;181(3):1025-9. doi: 10.1128/JB.181.3.1025-1029.1999.